Where should gastric biopsies be performed when areas of intestinal metaplasia are observed?

How should musculoskeletal biopsies be performed?

585 Biopsy refers to tissue sampling for histological examination, diagnosis, classification, and grading of a tumor. The goal of biopsy is to obtain a diagnostic tissue sample without complications, tumor spread, and compromise of future treatments.1,2 As a rule, all lesions should be biopsied as if they were malignant,2,3 and all soft tissue masses 3 cm or larger in diameter or growing lesion...

Supervisors Should Be More Vigilant When Their Students Are Writing an Article

در سخن سردبیری شماره مردادماه سال 1394 مجله دانشگاه، به ضرورت چاپ مقاله از پایان­نامه­های مقاطع مختلف تحصیلی اشاره کردیم و در همان جا، از اساتید راهنما درخواست کردیم که به جهت پرهیز از رویداد هرگونه تخلف پژوهشی توسط دانشجویان، نقش فعال­تری را در این زمینه ایفاء نمایند [1]. هم­چنین و پیش از آن، در  سخن سردبیری شماره بهمن و اسفندماه سال 1391 مجله دانشگاه، درخواست نموده بودیم که دانشجویان نقش فعال...

Should lung biopsies be performed in patients with severe asthma?

Asthma, and severe asthma, in particular, is increasingly recognised as a heterogeneous disease. Identifying these different phenotypes of asthma and assigning patients to phenotype-specific treatments is one of the current conundrums in respiratory medicine. Any diagnostic procedure in severe asthma (or any disease) should have two aims: 1) better understanding or identifying the diagnosis, an...

How are we addressing gastric intestinal metaplasia ?

Increased lysozyme expression in gastric biopsies with intestinal metaplasia and pseudopyloric metaplasia.

Lysozyme is an innate enzyme with potent non-immunological antibacterial properties in the upper intestinal tract. Lysozyme expression (ly-ex) was investigated in 80 consecutive sets of gastric biopsies having normal gastric mucosa (n=20), chronic gastritis (n=20), gastric intestinal metaplasia (IM, n=20), and pseudopyloric metaplasia (PpM, n=20). In biopsies with normal mucosa and with chronic...